Molecular Biology MCP MCP Servers

MCP servers for querying and analyzing biological and chemical databases (PDB, UniProt, ChEMBL, PubChem), protein structures, molecular properties, and computational chemistry/toxicology workflows. Does NOT include general bioinformatics analysis tools, sequence alignment, or non-database-backed prediction services unrelated to molecular structure and chemical data.

There are 45 molecular biology mcp servers tracked. 2 score above 50 (established tier). The highest-rated is genomoncology/biomcp at 59/100 with 458 stars.

Get all 45 projects as JSON

curl "https://pt-edge.onrender.com/api/v1/datasets/quality?domain=mcp&subcategory=molecular-biology-mcp&limit=20"

Open to everyone — 100 requests/day, no key needed. Get a free key for 1,000/day.

# Server Score Tier
1 genomoncology/biomcp

BioMCP: Biomedical Model Context Protocol

59
Established
2 nickzren/opentargets-mcp

MCP server for Open Targets Data

57
Established
3 biocontext-ai/registry

The BioContextAI Registry for biomedical MCP servers

49
Emerging
4 josefdc/Uniprot-MCP

UniProt MCP Server - Access comprehensive protein data via Model Context...

48
Emerging
5 tandemai-inc/rdkit-mcp-server

MCP server that enables language models to interact with RDKit through...

46
Emerging
6 Augmented-Nature/ChEMBL-MCP-Server

A comprehensive Model Context Protocol (MCP) server providing advanced...

46
Emerging
7 Augmented-Nature/PubChem-MCP-Server

A comprehensive Model Context Protocol (MCP) server for accessing the...

45
Emerging
8 longevity-genie/biothings-mcp

MCP (Model Context Protocol) server for biothings

45
Emerging
9 Augmented-Nature/Augmented-Nature-UniProt-MCP-Server

A comprehensive Model Context Protocol (MCP) server providing advanced...

44
Emerging
10 cyanheads/pubchem-mcp-server

A Model Context Protocol (MCP) server providing comprehensive LLM tools for...

44
Emerging
11 Augmented-Nature/PDB-MCP-Server

A Model Context Protocol (MCP) server that provides access to the Protein...

44
Emerging
12 biocontext-ai/knowledgebase-mcp

BioContextAI Knowledgebase MCP server for biomedical agentic AI

43
Emerging
13 EBISPOT/GrEBI

HPC aggregation pipeline and API/MCP server for LLM-mediated biomedical data...

41
Emerging
14 sebotic/cdk_pywrapper

A Python wrapper for the Chemistry Development Kit (CDK)

40
Emerging
15 Augmented-Nature/SureChEMBL-MCP-Server

A comprehensive Model Context Protocol (MCP) server for accessing the...

40
Emerging
16 spyrosze/mcp-openfoodtox

MCP server providing tools to access EFSA's comprehensive OpenFoodTox...

38
Emerging
17 ToxMCP/pbpk-mcp

MCP server for PBPK modeling workflows (simulation control + PK analytics).

36
Emerging
18 PabloPauling/posebusters-mcp-server

Unofficial MCP server for PoseBusters โ€“ validate molecular poses via HTTP or...

35
Emerging
19 ToxMCP/admetlab-mcp

MCP server for ADMETlab 3.0 (washing, ADMET prediction, rendering, CSV retrieval).

34
Emerging
20 hlydecker/ucsc-genome-mcp

An MCP server to interact with the UCSC Genome Browser API

33
Emerging
21 cyanheads/protein-mcp-server

MCP Server for 3D protein structural data retrieval & analysis from RCSB...

31
Emerging
22 tom832/chemdraw-server

This repository provides a unified FastAPI and MCP wrapper for an API that...

28
Experimental
23 dogeplusplus/bio-agents-mcp

MCP servers for Protein Data Bank, ChemBL, and other life science data...

27
Experimental
24 berntpopp/genefoundry

A modular registry for trustworthy, evidence-based genomic analysis powered...

25
Experimental
25 nickzren/mydisease-mcp

MCP server for MyDisease.info API

23
Experimental
26 nickzren/monarch-mcp

MCP server for Monarch Initiative Data

23
Experimental
27 ToxMCP/comptox-mcp

MCP server for the EPA CompTox API (chemical, exposure, hazard, predictive tooling).

23
Experimental
28 nickzren/mychem-mcp

MCP server for MyChem.info API

23
Experimental
29 ToxMCP/aop-mcp

MCP server for Adverse Outcome Pathway (AOP) discovery, semantics, and draft...

23
Experimental
30 ToxMCP/oqt-mcp

MCP server for OECD QSAR Toolbox workflows with structured outputs and PDF reports.

23
Experimental
31 nickzren/mygene-mcp

MCP server for MyGene.info API

23
Experimental
32 Genealogy-MCP/gramps-mcp

MCP server for Gramps Web โ€” search, browse, and manage your genealogy...

22
Experimental
33 Genealogy-MCP/gedcom-mcp

MCP server for GEDCOM files โ€” load, search, and explore your family tree...

22
Experimental
34 pansapiens/uniprot-unipressed-mcp

An MCP server to query Uniprot from your favorite LLM agent

21
Experimental
35 sakkkysaka/mcp-openfoodtox

๐Ÿงช Access EFSA's OpenFoodTox database for chemical hazards with a simple...

21
Experimental
36 agentcures/refua-mcp

Model Context Protocol server exposing typed Refua tools for folding,...

21
Experimental
37 genepattern/genepattern-mcp

MCP server that lets AI assistants (Claude, Cursor, Copilot) run GenePattern...

21
Experimental
38 borjanebbal/genomics-mcp

MCP server for genomics SNP trait lookup

21
Experimental
39 lukasmki/chemspace-mcp

MCP server enabling AI agents to search for synthesizable building blocks...

20
Experimental
40 Genealogy-MCP/familysearch-mcp

MCP server for the FamilySearch API โ€” search places, standardize dates,...

19
Experimental
41 Genealogy-MCP/wikitree-mcp

MCP server for the WikiTree API โ€” search profiles, explore ancestors and...

19
Experimental
42 Babajan-B/BioQC-MCP

Professional MCP server for FastQC and MultiQC quality control analysis with...

18
Experimental
43 AiAgentKarl/bioinformatics-mcp-server

MCP server for bioinformatics data โ€” genes, proteins, PubMed, ClinVar and...

14
Experimental
44 MacromNex/interpro_mcp

InterProScan MCP server for protein domain and functional analysis

13
Experimental
45 MacromNex/amber_mcp

AMBER MCP server for molecular dynamics simulations and analysis

13
Experimental