Medical Image Diffusion Diffusion Models

Diffusion models applied to medical imaging tasks including segmentation, synthesis, generation, and disease progression modeling of brain MRI, tumors, and histopathology. Does NOT include general medical AI, non-diffusion medical image processing, or non-medical image applications.

There are 47 medical image diffusion models tracked. The highest-rated is ge-xing/Diff-UNet at 44/100 with 192 stars.

Get all 47 projects as JSON

curl "https://pt-edge.onrender.com/api/v1/datasets/quality?domain=diffusion&subcategory=medical-image-diffusion&limit=20"

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#	Model	Score	Tier	Stars	Language
1	ge-xing/Diff-UNet Diff-UNet: A Diffusion Embedded Network for Volumetric Segmentation. (using...	44	Emerging	192	Python
2	LemuelPuglisi/BrLP [MICCAI, 2024] (Oral, RU @ MedIA Best Paper Award) Official implementation...	43	Emerging	122	Python
3	Warvito/generative_chestxray Repository to train Latent Diffusion Models on Chest X-ray data (MIMIC-CXR)...	39	Emerging	65	Python
4	jwmao1/MedSegFactory [ICCV 2025] MedSegFactory: Text-Guided Generation of Medical Image-Mask Pairs	39	Emerging	32	Python
5	GabrieleLozupone/LDAE Official PyTorch implementation of "Latent Diffusion Autoencoders: Toward...	38	Emerging	32	Jupyter Notebook
6	GlastonburyGroup/ImLatent Deep learning pipeline to obtain latent representation from images using 2D...	38	Emerging	4	Python
7	sauravdosi/mediffuse Imagine converting a CT scan into a photorealistic MRI—and back again—in...	37	Emerging	4	Python
8	Hejrati/cDAL Conditional diffusion model with spatial attention and latent embedding for...	35	Emerging	45	Python
9	0xallam/BrainLens Image Reconstruction from Brain fMRI imaging using Diffusion Models	32	Emerging	5	Python
10	gudaochangsheng/MaskUnet [CVPR 2025] Official PyTorch implementation of Not All Parameters Matter:...	32	Emerging	32	Python
11	jonasricker/aeroblade [CVPR2024] AEROBLADE: Training-Free Detection of Latent Diffusion Images...	31	Emerging	69	Python
12	haoningwu3639/MRGen [ICCV 2025] MRGen: Segmentation Data Engine for Underrepresented MRI Modalities	31	Emerging	39	Python
13	alawryaguila/CondDiff Pytorch code for "Conditional diffusion models for guided anomaly detection...	31	Emerging	2	Python
14	FabianFalck/unet-design Official PyTorch implementation of "A Unified Framework for U-Net Design and...	30	Emerging	20	Python
15	brAIn-science/CoCoLIT [AAAI, 2026] Official implementation of "CoCoLIT: ControlNet-Conditioned...	30	Emerging	10	Jupyter Notebook
16	GlastonburyGroup/CardiacDiffAE_GWAS Official code for the paper "Unsupervised cardiac MRI phenotyping with 3D...	30	Emerging	5	Python
17	TIO-IKIM/PhaseGen PhaseGen - Generate MRI raw data based on magnitudinal data	29	Experimental	12	Python
18	junjie-shentu/CXR-IRGen Implementation of the paper "CXR-IRGen: An Integrated Vision and Language...	29	Experimental	21	Python
19	AIM-KannLab/pediatric-brain-age Code for paper "Diffusion Deep Learning for Brain Age Prediction and...	28	Experimental	10	Python
20	PatrickSVM/Diffusion-Models-for-Brain-Tumor-MRI-Scans Training of Noise-to-Image Diffusion Model on Multi-Channel Brain Tumor MRI Scans.	27	Experimental	12	Jupyter Notebook
21	WenhaoYuan337/EMcopilot Related codes for Generative learning of morphological and contrast...	26	Experimental	7	Python
22	ZhngQ1/Measuring-Noise-Level-Dependence-in-Conditional-Image-Generation Quantitative framework for measuring how conditioning effectiveness varies...	26	Experimental	7	TeX
23	kunzhan/BrainGuard AAAI 2025 (Oral), BrainGuard: Privacy-Preserving Multisubject Image...	24	Experimental	21	Python
24	jhuldr/USB Unified Synthetic Brain Framework for Bidirectional Pathology–Healthy...	24	Experimental	14	Python
25	gmongaras/Latent_Diffusion_Model_Imagenet2012 A latent flow-based diffusion model trained on the 2012 ImageNet dataset...	23	Experimental	23	Python
26	reshalfahsi/medical-image-generation Medical Image Generation Using Diffusion Model	23	Experimental	2	Jupyter Notebook
27	faildeny/debiasing-cardiac-mri Code repository for paper: Fairness-Aware Data Augmentation for Cardiac MRI...	22	Experimental	5	Python
28	isno0907/LDMAE Latent Diffusion Models with Masked AutoEncoders (LDMAE) official code	22	Experimental	12	Python
29	SeyedMuhammadHosseinMousavi/Synthetic-Data-Generation-Algorithms Synthetic Data Generation Algorithms (VAE-GAN-Diffusion Model-LSTM-Copula)	21	Experimental	9	Python
30	pbarbarant/fmri2image_alignment A package for fMRI to image reconstruction using functional alignment	19	Experimental	3	Python
31	lyle-mlengineer/savannafaces A web service for generating authentic looking kenyan faces.	19	Experimental	—	CSS
32	risc-mi/braintumor-ddpm Using learned visual representations from diffusion models for brain tumor...	19	Experimental	20	Python
33	yXiangXiong/MR-Brainstem-Glioma-Synthesis ISMRM 2022 Abstract. A multi-task generative network for simultaneous...	19	Experimental	3	Python
34	anto18671/fairface-diffusion A diffusion model trained on FairFace with discrete conditioning on age,...	18	Experimental	1	Python
35	meanderinghuman/DiffuKnee A PyTorch implementation of a diffusion-model + U-Net pipeline for automated...	18	Experimental	1	Python
36	raghuveerbhat/BrightFieldDiffusion Predicting major subcellular structures from a single input transmitted...	18	Experimental	2	Python
37	Zenchiyu/diffusion Deep Learning Project on Diffusion Models for Image Generation	17	Experimental	1	Python
38	Parth-nXp/BrainDiffU-Net A decentralized, diffusion-based U-Net framework for privacy-preserving...	15	Experimental	—	Python
39	ZY-LIi/IEEE_TGRS_DEMAE Pre-train a Masked Autoencoder with the idea of Diffusion Models for...	13	Experimental	9	Python
40	hectorastrom/gaussian-glasses Making hidden objects classifier-legible through diffusion.	13	Experimental	2	Python
41	namanxkumar/fea-diffusion Image to Image FEA with Generative Models. Input images of a 2D geometry,...	11	Experimental	3	Jupyter Notebook
42	FinnBehrendt/Mahalanobis-Unsupervised-Anomaly-Detection Codebase for the paper Leveraging the Mahalanobis Distance to enhance...	11	Experimental	3	Python
43	5anjana/diffusion-downstream Trained a UNet model on the Lizard-v2 dataset to segment and classify six...	11	Experimental	1	Jupyter Notebook
44	federicobrancasi/neural-anomaly-metric-paper Anomaly detection approach for quality assessment of quantized diffusion...	11	Experimental	—	TeX
45	sydlevyjr/cs668-bmri-sdl CS 668 - Capstone Project - SDL	10	Experimental	1	Python
46	abdelnour13/images_generation_latent_diffusion_models This repository contains an implementation of latent diffusion models for...	10	Experimental	2	Python
47	reshalfahsi/medical-latent-diffusion-model Generating Medical Images with the Label-Conditioned Latent Diffusion Model...	10	Experimental	2	Jupyter Notebook