CHNFTQ/Capricorn
Capricorn: Enhancing Hi-C contact matrices for loop detection with a multi-view diffusion approach
Capricorn helps geneticists and molecular biologists get clearer, higher-resolution Hi-C contact maps from their raw data. It takes your existing Hi-C contact matrices, which can often be noisy or sparse, and enhances them by integrating additional chromatin features. The output is a "super-resolution" Hi-C matrix, making it easier to accurately identify crucial chromatin loops in genomes.
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Use this if you need to improve the clarity and detail of your Hi-C contact maps to better detect genomic loop structures from potentially low-coverage or noisy experimental data.
Not ideal if you are not working with Hi-C data or primarily need to analyze other types of genomic interactions like ChIP-seq or ATAC-seq.
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Language
Python
License
MIT
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Last pushed
May 14, 2025
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