masa-ue/RLfinetuning_Diffusion_Bioseq
Code for the tutorial/review paper for RL-based-fine-tuniing. In this code, we especially focus on the design of biological sequences like DNA (enhancers) and RNA (UTRs) design.
This project helps biological researchers design novel DNA (like enhancers) and RNA (like UTRs) sequences with specific desired activity levels. You provide a diffusion model for genetic sequences and a target activity level, and it outputs fine-tuned sequences predicted to achieve that activity. This is for scientists, genetic engineers, or bioinformaticians working on optimizing gene expression or therapeutic design.
158 stars. No commits in the last 6 months.
Use this if you need to generate biological sequences like DNA or RNA that are optimized for a specific functional property or activity level.
Not ideal if you are not working with biological sequences or do not have a way to measure the 'activity' or 'reward' of your desired sequence properties.
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Sep 15, 2024
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