pinellolab/DNA-Diffusion

🧬 Generative modeling of regulatory DNA sequences with diffusion probabilistic models 💨

54
/ 100
Established

This tool helps computational biologists and geneticists generate new, synthetic regulatory DNA sequences that are specific to certain cell types. You input existing data on chromatin accessible regions, and the project outputs novel DNA sequences (around 200bp long) that mimic the characteristics of real regulatory elements for specific cell types.

472 stars.

Use this if you need to create entirely new, functional-like regulatory DNA sequences for specific cell types to explore genetic mechanisms or test hypotheses without needing to synthesize actual DNA initially.

Not ideal if you're looking for a tool to analyze existing DNA sequences, identify known regulatory elements, or perform traditional sequence alignment.

genomics computational biology synthetic biology gene regulation bioinformatics
No Package No Dependents
Maintenance 10 / 25
Adoption 10 / 25
Maturity 16 / 25
Community 18 / 25

How are scores calculated?

Stars

472

Forks

60

Language

Python

License

Last pushed

Mar 02, 2026

Commits (30d)

0

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