Merck/Sapiens

Sapiens is a human antibody language model based on BERT.

63
/ 100
Established

This tool helps scientists and researchers in drug discovery by analyzing human antibody sequences. You input an incomplete or non-human antibody sequence, and it provides suggestions for amino acids to fill gaps or mutations to make the antibody more human-like. It's designed for antibody engineers and computational biologists working on therapeutic antibody development.

Available on PyPI.

Use this if you need to design, humanize, or evaluate the humanness of antibody sequences for therapeutic development.

Not ideal if you are working with non-antibody proteins or require analysis of antibody function beyond sequence humanness and design.

antibody-engineering drug-discovery biologics-development protein-design immunology-research
Maintenance 10 / 25
Adoption 9 / 25
Maturity 25 / 25
Community 19 / 25

How are scores calculated?

Stars

72

Forks

20

Language

Jupyter Notebook

License

MIT

Last pushed

Jan 22, 2026

Commits (30d)

0

Dependencies

3

Get this data via API

curl "https://pt-edge.onrender.com/api/v1/quality/embeddings/Merck/Sapiens"

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