THUNLP-MT/dyMEAN
This repo contains the codes for our paper "End-to-End Full-Atom Antibody Design"
This project provides an end-to-end system for designing full-atom antibody structures, focusing on crucial binding regions and overall protein stability. It takes existing antibody structural data (PDB files) and, through various modules, outputs optimized antibody designs with improved binding affinity and predicted complex structures. Researchers and scientists in drug discovery, immunology, and protein engineering fields can use this to accelerate the development of new therapeutic antibodies.
126 stars. No commits in the last 6 months.
Use this if you need to design novel antibodies, predict their complex structures, or optimize their binding affinity to targets.
Not ideal if you are solely interested in analyzing existing antibody structures or require a tool for general protein design outside of antibodies.
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126
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Language
Python
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MIT
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Last pushed
Feb 26, 2025
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