ICU Patient Risk Prediction ML Frameworks

Machine learning models for predicting adverse clinical outcomes (mortality, deterioration, sepsis, AKI, intubation need) in ICU patients using EHR data and clinical datasets like MIMIC. Does NOT include general health risk prediction, non-ICU settings, or single-disease diagnosis systems without outcome prediction focus.

There are 68 icu patient risk prediction frameworks tracked. 2 score above 50 (established tier). The highest-rated is rvandewater/YAIB at 64/100 with 93 stars.

Get all 68 projects as JSON

curl "https://pt-edge.onrender.com/api/v1/datasets/quality?domain=ml-frameworks&subcategory=icu-patient-risk-prediction&limit=20"

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#	Framework	Score	Tier	Stars	Language
1	rvandewater/YAIB 🧪Yet Another ICU Benchmark: a holistic framework for the standardization of...	64	Established	93	Python
2	YerevaNN/mimic3-benchmarks Python suite to construct benchmark machine learning datasets from the...	51	Established	874	Python
3	justin13601/ACES [ICLR 2025] ACES: Automatic Cohort Extraction System for Event-Streams	44	Emerging	40	Python
4	myADLM/ADLM-2025-Data-Challenge Build an AI Tool for Extracting Information from Laboratory Documentation	43	Emerging	12	—
5	cconsta1/SexEst SexEst is an open-source Streamlit web application for predicting biological...	43	Emerging	11	Python
6	Mubarraqqq/gnn-challenge This project focuses on predicting maternal-fetal health outcomes,...	42	Emerging	4	Python
7	futianfan/clinical-trial-outcome-prediction benchmark dataset and Deep learning method (Hierarchical Interaction...	41	Emerging	150	Python
8	yhzhu99/covid-ehr-benchmarks A Comprehensive Benchmark For COVID-19 Predictive Modeling Using Electronic...	41	Emerging	46	Python
9	AI4HealthUOL/MDS-ICU Repository for the paper 'A Multimodal Deep Learning Framework for...	41	Emerging	5	Python
10	MachineLearning-Nerd/Machine-Learning-for-Healthcare-Analytics Machine Learning (ML) has changed the way organizations and individuals use...	39	Emerging	15	HTML
11	BiomedSciAI/DPM360 Repository for Disease Progression Modeling workbench 360 - An end-to-end...	37	Emerging	19	JavaScript
12	Lrebaud/ICARE Individual Coefficient Approximation for Risk Estimation (ICARE) model	36	Emerging	18	Jupyter Notebook
13	mapo89/continuous-aki-predict Interpretable and continuous AKI prediction in the intensive care	35	Emerging	12	Jupyter Notebook
14	abhisheks008/Predicting-Death-Time-and-Mortality A Machine Learning Approach for Predicting the Death Time and Mortality	34	Emerging	8	Jupyter Notebook
15	vitaliy-ostapchuk93/disease-pattern-miner Disease Pattern Miner is a free, open-source mining framework for...	33	Emerging	12	Java
16	1AyaNabil1/Healthcare-Machine-Learning Explore our open-source repository focused on healthcare machine learning....	33	Emerging	5	Jupyter Notebook
17	hirenhk15/risk-models-for-medical-prognosis An End-to-end Machine Learning System with User Interface for predicting the...	33	Emerging	6	Jupyter Notebook
18	yhzhu99/pyehr COVID-19 EHR data analysis pipeline	32	Emerging	29	Python
19	javiersgjavi/tabular-mimic-iii repository for easy generation of tabulated dataset from the MIMIC-III database	32	Emerging	5	HTML
20	anondo1969/FedSepsis Repository for the journal article, 'FedSepsis: A Federated Multi-Modal Deep...	31	Emerging	7	Jupyter Notebook
21	javiersgjavi/sepsis-review Baseline to compare the performance of different models with sepsis data...	31	Emerging	7	HTML
22	vincenzorusso3/mimic-iv-benchmarks FDSML Course Project 2020/21	31	Emerging	15	Python
23	PERSIMUNE/PAC2022Marandi__DengueML_Plasma_Leakage code repository for a machine learning model for early prediction of plasma...	30	Emerging	2	R
24	bnarasimha21/patient-survival Machine learning model for predicting patient survival outcomes from clinical data	30	Emerging	1	Python
25	iheallab/apricotM This repository contains the official code for the paper "Real-time...	29	Experimental	16	Python
26	anneliset47/ml-pathogenicity.github.io Machine learning classification of genetic variants to predict...	29	Experimental	1	Python
27	AvatarJoshi/copd_project (Ongoing Project) Uses CDC data to map the burden of Chronic Obstructive...	28	Experimental	9	Jupyter Notebook
28	sanjatkanjilal/hospital_onset_infection_analyses Source code for analysis of the impact of environmental and patient-level...	28	Experimental	2	R
29	i6092467/pediatric-appendicitis-ml Using ML to predict the diagnosis, management, and severity of pediatric appendicitis	27	Experimental	12	R
30	nicolaDeCristofaro/predictive-models-in-healthcare Data Science & Machine Learning Project applied to Healthcare	27	Experimental	16	Jupyter Notebook
31	ejw-data/ml-myopia A variety of machine learning techniques used to identify nearsighted patients	25	Experimental	8	Jupyter Notebook
32	CDCgov/machine-learning-influenza-ferret-model Kieran et al. 2024 - Communication Biology - R code for machine learning in...	25	Experimental	—	R
33	Amario1306619051/Patient-Mortality-Prediction-Using-LSTM ## Patient Mortality Prediction Using LSTM 🏥🔍 Welcome to the Patient...	24	Experimental	5	Jupyter Notebook
34	Joyaji/reproducible-mortality-prediction 🩺 Predict in-hospital mortality using a reproducible deep learning model...	22	Experimental	—	Python
35	regularize-this/sepsis-progression-modeling Bayesian Modeling of Sepsis Progression in the ICU Using MIMIC-IV	22	Experimental	—	Jupyter Notebook
36	paolomaccallini-hub/CompareME Unsupervised clustering of common human diseases based on GWAS and WGS data,...	22	Experimental	—	R
37	Naomiteroh/Seasonal_Flu_Prediction_Analysis Machine learning classification project predicting seasonal flu vaccination...	22	Experimental	—	Jupyter Notebook
38	ctkqiang/Influenza-ML 本项目开发了一个基于机器学习的禽流感病毒(H5N1)预测系统，旨在通过分析历史数据和实时社交媒体信息，对禽流感疫情进行预测和风险评估。该系统采用决策树算法...	20	Experimental	6	Python
39	marcusosterberg/triage-at-home ML-testprojekt för att använda NLP-teknik för att klassificera, ge...	19	Experimental	3	Jupyter Notebook
40	daehan-lim/associative-classifier-mortality-prediction An interpretable associative classifier for predicting patient mortality...	19	Experimental	4	Jupyter Notebook
41	godseritesh/OptiHeart_Retinal_Insight_to_Cardiac_Health This repository contains an advanced machine learning solution for heart...	18	Experimental	2	Jupyter Notebook
42	CrezC/RespiForecast ML system predicting flu outbreaks 1-4 weeks ahead with 99.3% accuracy....	17	Experimental	—	Jupyter Notebook
43	WFLiu0327/Awesome-for-AI-in-Cardiovascular A detailed awesome for Artificial Intelligence in Cardiovascular	17	Experimental	1	—
44	nitin2468git/covid19-severity-prediction End-to-end healthcare AI pipeline on MIMIC-IV clinical data — SQL,...	15	Experimental	1	Jupyter Notebook
45	Koonarm/Early_SEPSIS_ML Machine learning models for early sepsis prediction using EMR data	15	Experimental	1	—
46	Majed-MD-AI/ATLAS-ICU-Deterioration-Prediction Clinical AI project for early ICU deterioration prediction	14	Experimental	—	Jupyter Notebook
47	KrishnaKJoshi1/icu-mortality-risk-prediction Machine Learning project predicting ICU mortality risk using EHR-derived...	14	Experimental	—	Jupyter Notebook
48	KODAK-CODER/Flu-Vaccine-Uptake-Prediction Predicting H1N1 and Seasonal Flu vaccine uptake using Random Forest...	14	Experimental	—	Jupyter Notebook
49	vipulvinit/Healthcare-Symptom-Pattern-Discovery Unsupervised ML pipeline for healthcare symptom pattern discovery using...	14	Experimental	—	Jupyter Notebook
50	ahmad-abotrab/patient_survival_prediction In-Hospital Mortality Prediction from Structured Clinical Data	14	Experimental	—	Jupyter Notebook
51	ValeriyaKunichik/triage-pro Early clinical risk prediction under epidemic conditions	14	Experimental	—	Jupyter Notebook
52	Troy-Kieran/Limited-heft-of-weight-based-outcomes-in-predicting-influenza-A-virus-disease-severity-in-ferrets Kieran et al. (under revision) - PLoS Computational Biology	14	Experimental	—	R
53	lcmrhodes/spot-sepsis-cascade Two-stage machine learning cascade and Shiny app for severe febrile illness...	14	Experimental	—	R
54	GitData-GA/h5n1 The study focuses on modeling and predicting H5N1 bird flu outbreaks in the...	14	Experimental	—	CSS
55	AhmedHassanGondal/Disease-Feature-Analysis Comparing TF-IDF vs One-Hot encoding for disease classification using KNN...	14	Experimental	—	Python
56	uh-joan/ct-outcome-predictor Clinical trial outcome predictor — 0.926 AUC-ROC on held-out Phase 2/3...	14	Experimental	—	Python
57	CareNX-Innovations-Pvt-Ltd/fetosense_auto Fetosense Auto brings automation and intelligence to portable fetal...	13	Experimental	—	Jupyter Notebook
58	UltiPro/DeathRiskAI DeathRiskAI created by Patryk 'UltiPro' Wójtowicz using Scikit Learn and Tensorflow.	13	Experimental	—	Jupyter Notebook
59	madhusai85/Heart-Disease-Prediction An advanced cardiovascular risk prediction system using Explainable AI...	13	Experimental	—	Jupyter Notebook
60	abhishek-ch/mimic-ai MIMICAI - Exploring MIMIC Data Using LLM and Open-WebUI	12	Experimental	8	Python
61	kevinchtsang/AAMOS-00-Starter Starter code to work with the AAMOS-00 dataset, a mobile health asthma...	11	Experimental	—	R
62	NajiaAhmadi/Benchmarking-Analysis-of-PLP-vs-MLR3 This repo contains analysis performed for paper "A comparative patient-level...	11	Experimental	4	R
63	TamimSaykat/icu-intubation-need-predictor End-to-end ICU intubation risk prediction system on MIMIC-IV!	11	Experimental	—	—
64	AYUSHSURYAVANSHI/Swine-Flu-Prediction-Project- This project predicts the likelihood of individuals receiving H1N1 and...	11	Experimental	3	Jupyter Notebook
65	tushar2704/Patient_Survival_Prediction Getting a rapid understanding of the context of a patient’s overall health...	11	Experimental	—	Jupyter Notebook
66	ShahbazShaddy/SepsisGuard-AI The repository SepsisGuard-AI by ShahbazShaddy is designed for developing an...	10	Experimental	2	HTML
67	eagomezc/Machine-Learning-and-RA-treatment This repository contains the script used to study blood pro-resolving...	10	Experimental	2	R
68	benjamin-milhet/FinalCountdown L'objectif de ce projet est la prédiction de la date de la mort d'un individu.	10	Experimental	2	TypeScript

Comparisons in this category

mimic3-benchmarks and mimic-iv-benchmarks (51 vs 31) covid-ehr-benchmarks and pyehr (41 vs 32)