Bitbol-Lab/DiffPALM
Differentiable Pairing using Alignment-based Language Models
This tool helps computational biologists and bioinformaticians accurately match interacting protein sequences (paralogs). By inputting multiple sequence alignments (MSAs), it leverages advanced language models to identify correct protein pairings, even when dealing with complex evolutionary relationships. This is particularly useful for researchers studying protein-protein interactions and co-evolutionary patterns.
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Use this if you need to determine which protein sequences from two different groups physically interact with each other, especially for paralogous proteins.
Not ideal if you are looking for a general-purpose protein sequence alignment tool or a simple homology search engine.
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24
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3
Language
Jupyter Notebook
License
Apache-2.0
Category
Last pushed
Jan 05, 2024
Commits (30d)
0
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