HelmchenLabSoftware/Cascade

Calibrated inference of spiking from calcium ΔF/F data using deep networks

58
/ 100
Established

This tool helps neuroscientists and biologists analyze calcium imaging data to understand neural activity. You input raw calcium imaging ΔF/F traces, and it translates them into precise spiking probabilities or discrete neural spikes, providing a clearer picture of neuronal firing. This is for researchers studying brain regions, spinal cord, or specific calcium indicators like GCaMP, who need accurate spike rate estimates without complex parameter tuning.

159 stars.

Use this if you need to accurately infer neuronal spike rates and discrete spikes from calcium imaging ΔF/F data to improve temporal resolution and denoise recordings.

Not ideal if your primary interest is in a different neuroscience technique, or if you require extensive manual parameter tuning for spike inference.

neuroscience research calcium imaging analysis neural activity inference brain research spinal cord studies
No Package No Dependents
Maintenance 10 / 25
Adoption 10 / 25
Maturity 16 / 25
Community 22 / 25

How are scores calculated?

Stars

159

Forks

51

Language

Jupyter Notebook

License

GPL-3.0

Last pushed

Feb 11, 2026

Commits (30d)

0

Get this data via API

curl "https://pt-edge.onrender.com/api/v1/quality/ml-frameworks/HelmchenLabSoftware/Cascade"

Open to everyone — 100 requests/day, no key needed. Get a free key for 1,000/day.