MLI-lab/DeepDeWedge

Self-supervised deep learning for denoising and missing wedge reconstruction of cryo-ET tomograms

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Emerging

This project helps cryo-electron tomography researchers improve the quality of their 3D images of biological samples. It takes noisy tomograms, which are 3D reconstructions with limited viewing angles (the 'missing wedge'), and processes them to produce clearer, more complete 3D structures, making it easier to visualize and analyze cellular components. Cryo-ET scientists, biologists, and structural biologists who work with electron microscopy data would use this.

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Use this if you need to simultaneously reduce noise and reconstruct missing information in your cryogenic electron tomograms to get a clearer picture of your biological samples.

Not ideal if you are not working with cryo-electron tomography data or if your primary need is general image denoising outside of this specific domain.

cryo-ET electron-microscopy structural-biology tomogram-reconstruction biological-imaging
Stale 6m No Package No Dependents
Maintenance 2 / 25
Adoption 8 / 25
Maturity 16 / 25
Community 18 / 25

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49

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13

Language

Jupyter Notebook

License

BSD-2-Clause

Last pushed

Jul 29, 2025

Commits (30d)

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