WGLab/DeepMod2
DNA 5mC methylation detection from Dorado or Guppy basecalled Oxford Nanopore reads
This tool helps researchers analyze DNA modifications, specifically 5mC methylation, from Oxford Nanopore sequencing data. It takes raw signal files (POD5 or FAST5) and basecalled BAM files as input, then identifies methylation sites and produces a new BAM file tagged with methylation information. Geneticists, molecular biologists, and epigenetics researchers can use this to understand gene regulation and cellular processes.
No commits in the last 6 months.
Use this if you are performing Oxford Nanopore sequencing and need to accurately detect DNA 5mC methylation patterns from your raw or basecalled reads.
Not ideal if you are working with other types of DNA modifications or sequencing platforms, as this tool is specifically designed for 5mC and Oxford Nanopore data.
Stars
61
Forks
5
Language
Jupyter Notebook
License
MIT
Category
Last pushed
Mar 05, 2025
Commits (30d)
0
Get this data via API
curl "https://pt-edge.onrender.com/api/v1/quality/ml-frameworks/WGLab/DeepMod2"
Open to everyone — 100 requests/day, no key needed. Get a free key for 1,000/day.
Higher-rated alternatives
google/deepvariant
DeepVariant is an analysis pipeline that uses a deep neural network to call genetic variants...
cgoliver/rnaglib
Toolkit for structure-based deep learning on RNA.
google/deepsomatic
DeepSomatic is an analysis pipeline that uses a deep neural network to call somatic variants...
Kuanhao-Chao/OpenSpliceAI
🤖 Open‑source deep-learning-based splice‑site predictor that decodes splicing patterns across species
Merck/deepbgc
BGC Detection and Classification Using Deep Learning