bioinfodlsu/PHIStruct
Published in Bioinformatics. Phage-host interaction prediction tool that incorporates protein structure information in representing receptor-binding proteins (RBPs). It improves performance especially for phages with RBPs that have low sequence similarity to those of known phages
PHIStruct helps researchers identify which bacterial hosts a bacteriophage (phage) will infect. By analyzing the 3D structure of a phage's receptor-binding proteins, it predicts the most likely host bacterial genera. This tool is designed for microbiologists, virologists, or biotechnology researchers working with phages and bacterial interactions.
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Use this if you need to predict the bacterial host of a phage, especially when its receptor-binding proteins have low sequence similarity to known phages.
Not ideal if you primarily rely on sequence-only data and do not have or cannot generate 3D protein structure information.
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MIT
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Jul 13, 2025
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