bnediction/scBoolSeq

scBoolSeq: scRNA-Seq data binarisation and synthetic generation from Boolean dynamics

30
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Emerging

This tool helps biologists and geneticists convert complex single-cell RNA sequencing (scRNA-Seq) data into a simplified, interpretable format, showing gene activity as either 'on' or 'off'. It takes raw scRNA-Seq expression matrices and outputs binarized gene expression states. Researchers analyzing gene regulatory networks or cell state transitions will find this useful.

No commits in the last 6 months. Available on PyPI.

Use this if you need to simplify high-dimensional scRNA-Seq data into clear, binary gene activity states or generate synthetic scRNA-Seq data based on theoretical Boolean network models.

Not ideal if your primary goal is differential expression analysis or visualizing continuous gene expression levels without binarization.

single-cell transcriptomics gene expression analysis computational biology systems biology gene regulatory networks
No License Stale 6m
Maintenance 2 / 25
Adoption 5 / 25
Maturity 17 / 25
Community 6 / 25

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Language

Python

License

Last pushed

Aug 13, 2025

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