denisbeslic/denovopipeline
Pipeline for de novo peptide sequencing (Novor, DeepNovo, SMSNet, PointNovo, Casanovo) and assembly with ALPS.
This tool helps proteomic researchers and bioinformaticians identify unknown peptide sequences by analyzing tandem mass spectrometry data. It takes your raw mass spectrometry files (like .raw, .mzxml, or .mzml) and converts them into a standardized format. Then, it runs multiple de novo sequencing algorithms to predict peptide sequences, providing you with a comprehensive summary of these predictions for further analysis, especially useful for assembling monoclonal antibody sequences.
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Use this if you need to determine the amino acid sequences of peptides directly from tandem mass spectrometry data, especially for complex samples like monoclonal antibodies, without relying on a pre-existing protein database.
Not ideal if you primarily need to identify peptides by searching against a known protein sequence database, as this tool focuses on discovering novel or unknown sequences.
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Language
Python
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Last pushed
Feb 23, 2024
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