google/deepsomatic

DeepSomatic is an analysis pipeline that uses a deep neural network to call somatic variants from tumor-normal and tumor-only sequencing data.

56
/ 100
Established

This tool helps researchers and clinicians accurately find somatic variants from patient tumor and normal tissue sequencing data. It takes aligned DNA sequencing reads and uses deep learning to identify genetic mutations specific to the tumor, producing a standard VCF or gVCF file listing these variants. Cancer researchers and clinical geneticists would use this to understand tumor genetics.

296 stars.

Use this if you need to precisely identify cancer-specific genetic mutations from tumor-normal or tumor-only DNA sequencing data.

Not ideal if you are looking for germline (inherited) variants or a tool for general genomic analysis unrelated to somatic mutations.

cancer-genetics somatic-variant-calling tumor-sequencing genomic-analysis precision-medicine
No Package No Dependents
Maintenance 10 / 25
Adoption 10 / 25
Maturity 16 / 25
Community 20 / 25

How are scores calculated?

Stars

296

Forks

46

Language

License

BSD-3-Clause

Last pushed

Mar 05, 2026

Commits (30d)

0

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