pengxingang/TEIM
TEIM: TCR-Epitope Interaction Modeling
This project helps immunologists and biomedical researchers understand how T-cell receptors (TCRs) interact with specific disease-related antigens (epitopes). By inputting the primary sequences of TCR CDR3βs and epitopes, it predicts either the likelihood of a successful binding interaction or detailed residue-level contact probabilities and distances between them. This is valuable for researchers studying immune responses, vaccine development, or personalized medicine.
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Use this if you need to predict whether a specific T-cell receptor will bind to an epitope, or to understand the precise interaction points at the residue level for designing targeted immunotherapies or vaccines.
Not ideal if you are looking to predict interactions for other receptor types or if you don't have the primary sequences of the TCR CDR3βs and epitopes.
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Language
Python
License
MIT
Category
Last pushed
Jul 26, 2023
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