yizhak-lab-ccg/scXpand
scXpand: detection of T-cell clonal expansion from single-cell RNA sequencing
This tool helps cancer researchers and immunologists analyze single-cell RNA sequencing data to identify T-cell clonal expansion, which is crucial for understanding immune responses in cancer. It takes your raw UMI counts from single-cell RNA sequencing of T-cells as input and outputs predictions about which T-cells have clonally expanded. This is designed for scientists working with immunology and oncology data.
Available on PyPI.
Use this if you need to detect T-cell clonal expansion from single-cell RNA sequencing data without needing paired T-cell receptor (TCR) sequencing.
Not ideal if your data is not raw UMI counts from T-cells or if your gene identifiers are not Ensembl IDs, as it requires specific input formats.
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4
Language
Python
License
MIT
Category
Last pushed
Dec 16, 2025
Commits (30d)
0
Dependencies
21
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