google/deepconsensus

DeepConsensus uses gap-aware sequence transformers to correct errors in Pacific Biosciences (PacBio) Circular Consensus Sequencing (CCS) data.

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Established

DeepConsensus helps genetic researchers and bioinformaticians improve the accuracy of DNA sequencing data from Pacific Biosciences (PacBio) machines. It takes raw 'subreads' generated by a PacBio sequencer and processes them to produce highly accurate, 'corrected reads' in FASTQ format. This allows for more reliable downstream analyses like variant calling and genome assembly, leading to a higher yield of useful sequencing data.

256 stars. No commits in the last 6 months. Available on PyPI.

Use this if you are working with PacBio sequencing data and need to enhance the accuracy of your reads for more reliable genetic analysis or genome assembly.

Not ideal if your `ccs` settings filter out reads with a predicted quality below 20 by default, as DeepConsensus works best with unfiltered raw subreads.

genomic-sequencing bioinformatics DNA-sequencing variant-calling genome-assembly
Stale 6m
Maintenance 0 / 25
Adoption 10 / 25
Maturity 25 / 25
Community 18 / 25

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Stars

256

Forks

38

Language

Python

License

BSD-3-Clause

Last pushed

Mar 11, 2025

Commits (30d)

0

Dependencies

7

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